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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
10 DPC

10 matching records from 10 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nkx2-1  NK2 homeobox 1   (Synonyms: T/EBP, thyroid-specific enhancer-binding protein, thyroid transcription factor-1, tinman, Titf1, Ttf-1)
Results  Reference
1*J:85473 Corbin JG, Rutlin M, Gaiano N, Fishell G, Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development. 2003 Oct;130(20):4895-906
1J:169134 Domyan ET, Ferretti E, Throckmorton K, Mishina Y, Nicolis SK, Sun X, Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development. 2011 Mar;138(5):971-81
1J:104223 Fagman H, Andersson L, Nilsson M, The developing mouse thyroid: embryonic vessel contacts and parenchymal growth pattern during specification, budding, migration, and lobulation. Dev Dyn. 2006 Feb;235(2):444-55
1J:292005 Kim E, Jiang M, Huang H, Zhang Y, Tjota N, Gao X, Robert J, Gilmore N, Gan L, Que J, Isl1 Regulation of Nkx2.1 in the Early Foregut Epithelium Is Required for Trachea-Esophageal Separation and Lung Lobation. Dev Cell. 2019 Dec 16;51(6):675-683.e4
1*J:229458 Loebel DA, Plageman TF Jr, Tang TL, Jones VJ, Muccioli M, Tam PP, Thyroid bud morphogenesis requires CDC42- and SHROOM3-dependent apical constriction. Biol Open. 2016;5(2):130-9
1J:66247 Naltner A, Wert S, Whitsett JA, Yan C, Temporal/spatial expression of nuclear receptor coactivators in the mouse lung. Am J Physiol Lung Cell Mol Physiol. 2000 Dec;279(6):L1066-74
1*J:95017 Parlato R, Rosica A, Rodriguez-Mallon A, Affuso A, Postiglione MP, Arra C, Mansouri A, Kimura S, Di Lauro R, De Felice M, An integrated regulatory network controlling survival and migration in thyroid organogenesis. Dev Biol. 2004 Dec 15;276(2):464-75
1J:111617 Que J, Choi M, Ziel JW, Klingensmith J, Hogan BL, Morphogenesis of the trachea and esophagus: current players and new roles for noggin and Bmps. Differentiation. 2006 Sep;74(7):422-37
1*J:60228 Yuan B, Li C, Kimura S, Engelhardt RT, Smith BR, Minoo P, Inhibition of distal lung morphogenesis in Nkx2.1(-/-) embryos. Dev Dyn. 2000 Feb;217(2):180-90
1*J:35560 Zhou L, Lim L, Costa RH, Whitsett JA, Thyroid transcription factor-1, hepatocyte nuclear factor-3beta, surfactant protein B, C, and Clara cell secretory protein in developing mouse lung. J Histochem Cytochem. 1996 Oct;44(10):1183-93

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory